Endocrine Abstracts

Anabolic agents are used to enhance performance through their effects on muscle mass, strength, and stamina. The prevalence of anabolic steroid use is difficult to quantify amongst the general population, but estimates derived from anonymous questionnaire studies in various populations suggest use may be common. Up to 4% of 18 years old American males have reported use at least once. Reported use of these agents rises significantly amongst army recruits and further still in el...

Improvements in cancer therapy have led to increasing numbers of patients surviving complex conditions. A multidisciplinary approach using new treatment modalities allow more aggressive therapy and a greater risk in the long-term to pituitary function. Damage to the hypothalamic pituitary axis has traditionally resulted from the underlying lesion, surgical intervention and radiotherapy. Traditional chemotherapeutic agents have not been implicated. The effect radiation has upon...

Background: Increasing numbers of children and adults are surviving cancer and living with the consequences of their disease or its treatment. The commonest long term consequences observed following childhood cancer are endocrine and there is a growing body of evidence indicating that adults treated for malignant disease are also at risk of endocrine dysfunction.Aim: To determine the involvement of Endocrinologists in the management of cancer survivors a...

A 61-year-old man presented to his primary care service with complains of frequent hot flushes, dizziness and headache. Following initial screening, an incidental pituitary lesion was diagnosed on computed tomography (CT) scan and hence was referred to specialist review. Further detailed history revealed similar presentation with dizziness and hot flushes two and a half years ago. He was then diagnosed with essential hypertension after a negative work-up for Cushing disease. H...

Aim: To evaluate the current service provisions and provide action plan for improvement within the YAE service.Methods: A friends and family questionnaire given to all patients attending the YAE service from October 2018 – January 2019. Survey questions included: whether they thought this was a good clinic for friends and family to be looked after in, what we did well and what we could do better. For YA patients transferring from children’s s...

Lymphocytic hypophysitis (LyH) is a rare condition often associated with pregnancy (usually presenting in the last month of pregnancy or in the first two post-partum months). We describe a very rare case of recurrent LyH during two pregnancies.A 25-years old woman presented in 7/2003 with a 6-week history of headaches and a 2-week history of visual deterioration whilst 38 weeks pregnant. Bitemporal hemianopia was co...

Lymphocytic hypophysitis (LyH) is a rare condition often associated with pregnancy (usually presenting in the last month of pregnancy or in the first two post-partum months). We describe a very rare case of recurrent LyH during two pregnancies.A 25-years old woman presented in 7/2003 with a 6-week history of headaches and a 2-week history of visual deterioration whilst 38 weeks pregnant. Bitemporal hemianopia was co...

Background: Turner syndrome (TS) is associated with significant morbidity and a reduction in life expectancy. National guidelines have been developed to support the management of adult patients with TS but little is known about their implementation. We therefore sought to compare the management of patients with TS seen within a single tertiary referral centre by endocrinology, either general-purpose or Turner-specific clinics (TSC), or by other specialties.<p class="abstex...

Hypertension is the most commonly recognised cardiac manifestation of a phaeochromocytoma. There are however a variety of other cardiac presentations including arrhythmias and the increasingly reported Takotsubo cardiomyopathy. We present the case of a female patient presenting acutely to the general medical take who was found to have cardiac arrhythmias and transient left ventricular dysfunction.The initial presentation was breathlessness, chest pain, s...

Over the last 10 years there have been significant advances in stem cell transplantation (SCT) in adults for haematological malignancies leading to improved survival. Conditioning regimes prior to transplantation often utilise high dose chemotherapy and/or total body irradiation (TBI). Significant endocrinopathies have been reported amongst children undergoing SCT. We report the effect of SCT during adult life on endocrine function.Basal hormone levels w...